Thursday, May 21, 2020

Elizabeth Key and Her History-Changing Lawsuit

Elizabeth Key (1630 - after 1665) is a key figure in the history of American chattel slavery. She won her freedom in a lawsuit in 17th century colonial Virginia, and her lawsuit may have helped inspire laws making slavery a hereditary condition. Heritage Elizabeth Key was born in 1630, in Warwick County, Virginia. Her mother was a slave from Africa who is unnamed in the record. Her father was an English planter living in Virginia, Thomas Key, who arrived in Virginia before 1616. He served in the Virginia House of Burgesses, the colonial legislature. Accepting Paternity In 1636, a civil case was brought against Thomas Key, alleging that he had fathered Elizabeth. Such suits were common to get a father to accept responsibility to support a child born out of marriage, or to ensure that the father would help to get the child an apprenticeship. Key first denied paternity of the child, claiming that a â€Å"Turk† had fathered the child. (A â€Å"Turk† would have been a non-Christian, which could affect the slave status of the child.) He then accepted paternity and had her baptized as a Christian. Transfer to Higginson At about the same time, he was planning to go to England—perhaps the suit was filed to ensure that he accepted paternity before he left—and he placed the 6-year-old Elizabeth with Humphrey Higginson, who was her godfather. Key specified a term of indenture of nine years, which would bring her to the age of 15, a common time for indenture terms or apprentice terms to expire. In the agreement, he specified that after 9 years, Higginson was to take Elizabeth with him, give her a â€Å"portion,† and then free her to make her own way in the world. Also included in the instructions was that Higginson treat her like a daughter; as later testimony put it, â€Å"user her more Respectfully than a Common servant or slave.† Key then sailed for England, where he died later that year. Colonel Mottram When Elizabeth was about ten years old, Higginson transferred her to a Colonel John Mottram, a justice of the peace—whether it was a transfer or sale is not clear—and he then moved to what is now Northumberland County, Virginia, becoming the first European settler there. He founded a plantation he called Coan Hall. About 1650, Col. Mottram arranged for 20 indentured servants to be brought from England. One of those was William Grinstead, a young lawyer who indentured himself to pay for his passage and work that off during the term of indenture. Grinstead did legal work for Mottram. He also met and fell in love with Elizabeth Key, still held as a bond servant to Mottram, though it was by that time 5 or more years beyond the term of the original agreement between Key and Higginson. Even though Virginia law at that time forbid indentured servants from marrying, having sexual relations or having children, a son, John, was born to Elizabeth Key and William Grinstead. Filing Suit for Freedom In 1655, Mottram died. Those settling the estate assumed that Elizabeth and her son John were slaves for life. Elizabeth and William filed suit in court to recognize both Elizabeth and her son as already free. At the time, the legal situation was ambiguous, with some tradition assuming all â€Å"Negros† were slaves no matter the status of their parents, and other tradition assuming English common law where bondage status followed that of the father. Some other cases held that black Christians could not be slaves for life. The law was especially ambiguous if only one parent was an English subject. The suit was based on two factors: first, that her father was a free Englishman, and under English common law whether one was free or in bondage followed the status of the father; and second, that she had been â€Å"long since Christened† and was a practicing Christian. A number of people testified. One resurrected that old claim that Elizabeth’s father was a â€Å"Turk,† which would have meant neither parent was an English subject. But other witnesses testified that from a very early time, it was common knowledge that Elizabeth’s father was Thomas Key. The key witness was an 80-year-old former servant of Key, Elizabeth Newman. The record also showed that she had been called Black Bess or Black Besse. The court found in her favor and granted her freedom, but an appeal court found that she was not free, because she was a â€Å"Negro.† General Assembly and Retrial Then Grinstead filed a petition for Key with the Virginia General Assembly. The Assembly formed a committee to investigate the facts, and found â€Å"That by the Comon Law the Child of a Woman slave begot by a freeman ought to be free† and also noted that she had been christened and was â€Å"able to give a very good account of her fayth.† The Assembly returned the case to a lower court. There, on July 21, 1656, the court found that Elizabeth Key and her son John were in fact free persons. The court also required that the Mottram estate give her â€Å"Corn Clothes and Satisfaction† for her having served many years beyond the end of her term of service. The court formally â€Å"transferred† to Grinstead â€Å"a maid servant†. That same day, a marriage ceremony was performed and recorded for Elizabeth and William. Life in Freedom Elizabeth had a second son by Grinstead, named William Grinstead II. (Neither son’s birth date is recorded.) Grinstead died in 1661, after only five years of marriage. Elizabeth then married another English settler named John Parse or Pearce. When he died, he left 500 acres to Elizabeth and her sons, which allowed them to live out their lives in peace. There are many descendants of Elizabeth and William Grinstead, including a number of famous people (the actor Johnny Depp is one). Later Laws Before the case, there was, as outlined above, some ambiguity in the legal status of the child of a woman who was in bondage and a free father. The assumption of the Mottram estate that Elizabeth and John were slaves for life was not without precedent. But the idea that all of African descent were permanently in bondage was not universal. Some wills and agreements by owners specified terms of service for African slaves, and also specified land or other goods to be granted at the end of the term of service to aid in their new life as fully free persons. For example, a woman, Jone Johnson, daughter of one Anthony Johnson identified as a Negro, was given 100 acres of land by the Indian ruler Debeada in 1657. Key’s suit won her freedom and established the precedence of the English common law about a child born to a free, English father. In response, Virginia and other states passed laws to override the common law’s assumptions. Slavery in America became more solidly a race-based and hereditary system. Virginia passed these laws: 1660: the term of indentured servitude was limited to five years—for servants from a Christian country1662: a child’s status as free or bond (slave) status was to follow the mother’s status, contrary to English common law1667: being a Christian did not alter status of bondage1670: prohibited Africans from importing any bonded laborers from anywhere (Africa or England included)1681: children of a European mother and African father were to be in bondage to age 30 In Maryland: 1661: a law was passed making all African Americans in the colony slaves, and all African Americans slaves at birth whatever the status of the parents1664: a new law outlawed marriages between European or English women and African (Negro/black) men Note: while the term â€Å"black† or â€Å"Negro† was sometimes used for Africans from the beginning of the presence of people of African descent in colonial America, the term â€Å"white† came into legal usage in Virginia about 1691, with a law referring to â€Å"English or other white women.† Before that, each nationality was described. In 1640, for instance, a court case described a â€Å"Dutchman,† a â€Å"Scotch man† and a â€Å"Negro,† all bond servants who escaped to Maryland. An earlier case, 1625, referred to a â€Å"Negro,† a â€Å"Frenchman,† and â€Å"a Portugall.† More about the early history of black or African women in what is now the United States, including how laws and treatment evolved: Timeline of African American History and Women Also known as: Elizabeth Key Grinstead; due to spelling variations common at the time, last name was variously Key, Keye, Kay and Kaye; married name was variously Grinstead, Greensted, Grimstead, and other spellings; final married name was Parse or Pearce Background, Family: Mother: not namedFather: Thomas Key (or Keye or Kay or Kaye) Marriage, Children: husband: William Grinstead (or Greensted or Grimstead or other spellings) (married July 21, 1656; indentured servant and lawyer)children:John GrinsteadWilliam Grinstead IIhusband: John Parce or Pearce (married about 1661)

Wednesday, May 6, 2020

The Youngest US President ever to Take Office - 784 Words

John F. Kennedy was voted into office during the election of 1960. To date, Kennedy is the youngest person to be elected President. Surprisingly, at the start of the campaign, Kennedy was a long shot to win the Democratic nomination. Without a distinguished presence in the political world and the stigma of being Roman Catholic, Kennedy had a lot of ground to conquer. In not just politics, but society, religion is and was a controversial issue. Kennedy, who was Catholic, struggled against critics who were anti-Catholicism. It was often insisted that Kennedy would turn to the pope for orders and therefore run our country based upon the Church. Kennedy overcame this obstacle by reassuring voters he would not act according to the Church†¦show more content†¦As a nation that is expected to be the leaders of other nations, he would not settle for second. In the case of exploring space, that was exactly where we were. The Soviet Union was far ahead of the United States in its space program. With Project Apollo, Kennedy was determined to play catch up and asked congress to invest more that twenty-two billion dollars into the project. The end goal was to have an American man on the moon before the end of the decade. Neil Armstrong was that man in 1969. Not only was the Soviet Union viewed as a threat with their space program being more advance, but they also had nuclear missile sites being built. An American spy plane secretly photographed evidence that both Cuba and the Soviet Union were building nuclear missile sites. President Kennedy remained collected and directed that a naval blockade was placed around Cuba which would prevent the Soviets from obtaining more military supplies. On the brink of what could have been a nuclear war, there was an agreement made, the Soviets agreed to dismantle their weapons sites in exchange for a pledge from the United States not to invade Cuba. Tension slowly began to lessen as time passed and the agreement remained respected. Another one of Kennedy’s problems he was confronted during Presidency was racial discrimination. In 1954 the U.S. Supreme Court had ruled that segregation in public schools would be no longerShow MoreRelatedEssay on John F. Kennedy Inaugural Speech Analysis666 Words   |  3 PagesJohn F. Kennedy once said, â€Å"I am not the Catholic candidate for President. I am the Democratic Partys candidate for President, who happens also to be a Catholic.† In this single sentence, he uses a method of Aristotle’s persuasive speech making. One of the greatest examples of using rhetorical strategies is indeed John F. Kennedy’s inaugural address of 1961. John F. Kennedy uses diction, syntax, and Aristotle’s method of persuasion in his inaugural address that not only made it uniquely his ownRead MoreEssay Jfk Informative Speech Outline869 Words   |  4 Pagesinformation on President John F. Kennedy. The speech will provide a history of President Kennedy’ s life, the memorable points of his presidency and why he is an inspiration. Specific Purpose: To share with them his early life, his political career, his load of presidency, his tragic death, and his inspiration. Thesis Statement: President Kennedy proved to be one of the most remembered Presidents of America and inspires everyone, especially me. Preview statement: President John F. KennedyRead MorePresident Roosevelt s President Of The United States Essay1267 Words   |  6 PagesWhen President McKinley was assassinated Vice President Theodore Roosevelt became President of the United States at the age of 43. He is the youngest president in our nation’s history. Though President Roosevelt was young with fresh ideas filled with high energy as you will see that even after he became president he continued to do some things he enjoyed in his life. Roosevelt while still in the presidency, he continued to box inside the White House. In one of those instances while sparing he sparedRead MoreA Brief Look at John F. Kennedy835 Words   |  4 Pagesâ€Å" A famous quote spoken by a U.S President whose term of office was cut short by a belligerent man. John F. Kennedy or JFK would grow to become one of the United States’s smartest and youngest Presidents in history. Unfortunately for JFK his life and term as President was cut short after being assassinated by Lee Harvey Oswald. Although JFK did not serve a full term as President he affected our nation in many positive ways and was on the best presidents we ever had. John Fitzgerald Kennedy alsoRead MoreJohn F. Kennedy s Speech1243 Words   |  5 PagesBeing the youngest president elected and inheriting a war amounted to a lot of pressure alone for John F. Kennedy. Many have questioned if John F. Kennedy was the man to lead the country. In order to answer that question he gave a memorable inaugural address to make his critiques rethink their doubts. Kennedy’s speech is known as one of the most powerful speeches because of his of rhetorical strategies. Of course being the youngest president there’s a ton of pressure on Kennedy but with all theRead MoreJohn F. Kennedy: A Legacy Never Forgotten1377 Words   |  6 Pages Forgive your enemies, but never forget their names(Brainy Quotes). John F Kennedy said this during one of his speeches, and ironically no one will ever forget the name of the person who murdered him, Lee Harvey Oswald, an enemy of the American Public. When Kennedy ran for office, he had to seem like the more experienced candidate and appeal to all of the people. During his speeches, Kennedy engaged his audiences and they hung on his every word. However, the tragic event of his assassinationRead MoreThe Cuban Missile Crisis : Background1620 Words   |  7 Pagesas North Atlantic Alliance. NATO was intergovernmental military alliance compacted based by the North Atlantic Treaty signed on 4, 1949. The NATO a system of defense and if a country that was being attack by another country or external party and who ever was part of the NATO would have to send soldiers to the April country and help them fight of the invade. The NATO was also used during the Korean War when North Korea in vaded South Korea on Saturday, 24 June 1950. NATO is going till this day and hasRead MoreThe Leadership Styles And Behavioral Analysis1532 Words   |  7 Pagesâ€Å"Let us not seek the Republican answer or the Democratic answer but the right answer. Let us not seek to fix the blame for the past—let us accept our own responsibility for the future† -John F. Kennedy, 35th US President. This paper describes about the Leadership styles and Behavioral analysis of former U.S. president John F. Kennedy. Elected in 1960 as the 35th president of the United States, John F. Kennedy was the youngest man to hold that office. He was born on May 29, 1917, in BrooklineRead MoreDon t Dwell On The Inner Darkness Of Yourself887 Words   |  4 Pagesof yourself† (TR, An American Lion) We mourned the death of President William McKinley in 1901 after being assassinated. It was my fate of becoming the youngest President to take the office. Many people questioned my bold personality some accused me of bigotry. Me? Teddy Roosevelt? I prefer to be known as â€Å"TR†, the President to be known in history (1901-1909) as â€Å"The American Lion.† Our new President brought passion and power to the office, courageously leading the American people and Congress towardRead MoreThe Secret Military Installation On The Planet1663 Words   |  7 Pagesindividuals who perceive their importance greater than that of others. Historically, conspiracies associated with the United States government cause citizens to question their elected leaders. Broken trust requires many months and years to rebuild, if ever it can be. â€Å"Less than one hundred miles from Las Vegas, Nevada is the most famous secret military installation on the planet† (â€Å"Area†). â€Å"The actual area cannot be found on most maps, at least not those accessible to the public† (â€Å"Brannan†). â€Å"There

Critical Study of Alcohol and Hepatocytes Cell Necrosis Free Essays

Introduction The tissue shows vast inflammation, there are large gaps in between the hepatocytes due to cell necrosis and the hepatocytes remaining are large and swollen. There are fatty deposits throughout the tissue and fibrous structures present which are most likely collagen. The hepatocytes themselves are not only swollen but have the presence of globular material within. We will write a custom essay sample on Critical Study of Alcohol and Hepatocytes Cell Necrosis or any similar topic only for you Order Now This is identified as Mallory bodies, seen in cases of alcoholic hepatitis. These globules are aggregates of intermediate filaments in the cytoplasm which have resulted from hepatocyte injury. Neutrophils can be seen in the sample which is the likely cause of inflammation. These would have been called to the tissue due to the necrosis of the hepatocytes and the presence of cellular debris within the lobules [1]. An infiltration of macrophages can be seen which would also be due to the debris present. The first stage of alcoholic liver disease is the increase of fatty deposits in the liver. Heavy alcohol consumption causes the production of large fatty globules a process known as macrovesicular steatosis collecting in the liver cells. Ethanol consumed is metabolised by alcohol dehydrase in the mitochondria into toxic acetaldehyde which is metabolised by aldehyde dehydrogenase into acetic acid [1][2][3]. The production of acetaldehyde causes a higher NADH: NAD ratio which is the main mechanism in the development of this condition. This NADH production causes increase in lipogenesis and a decrease in fatty acid oxidation. The higher levels of fatty acids signal the hepatocytes to compound glycerol into triglycerides [3]. This is seen in the first stage of liver damage known as alcoholic hepatitis [2]. Excess alcohol intake can also cause hepatocyte injury via oxidative stress from increased NADH production in which free radicals damage the hepatocytes (increased production by the k upffer cells); and from lipid peroxidation where acetylhyde binds to proteins forming adducts [1]. This binding triggers humoral and cellular immune responses resulting in tissue injury. There is an increase in pro inflammatory cytokines such as tumour necrosis factor and interleukin -6 and a decrease in anti inflammatory cytokines such as interleukin -4 [1]. These cytokines in particularly TNF are secreted by the kupffer cells (macrophages) located in the liver. They’re activated by the increased levels of endotoxin released from the breakdown of alcohol by intestinal bacteria; this binds to the CD14 receptor on their surface initiating response. The release of these cytokines leads to the hepatic stellate cells producing increased levels of collagen which leads to liver fibrosis and also causes destructive damage to the hepatocytes. This leads to the last stage of liver disease known as cirrhosis which can occur in prolonged alcoholic hepatitis, seen in 40% of cases [1][4] . Individuals suffering with alcoholic hepatitis have an increase in serum bilirubin due to the inability of the damaged liver to process it. Bilirubin is normally removed from the blood by the liver, processed by it and released into the bile [4][5]. They’ll also have prolonged prothrombin time which reflects decreased hepatic synthetic function [4][5]. A number of clotting factor proteins are produced in the liver so an increase in coagulation time suggests a decrease in these factors indicating dysfunction of the liver. Decreased serum albumin can be observed in cases of liver injury as this is the main protein produced in the liver. Thyroid tests can indicate liver dysfunction such as testing for T3- triiodothrynonine which appears decreased in individuals with alcoholic hepatitis and is proportional to the level of damage[6][4]. There is also a decrease in serum cholesterol level seen in this condition. In cases where excessive alcohol consumption is not the cause of hepatitis further testing should be done. Individuals can develop hepatitis due to drug use as currently 1000 drugs are seen to be hepatotoxic [7]. There must be a chronic correlation seen between when the medicine was first taken and the observation of hepatitis. There must also be a correlation between the removal of medication and the recession of the condition [4]. Other causes of hepatitis must also be tested for such as viral hepatitis. There are 5 subsets of viral hepatitis A, B, C, and the less common D and E forms. Hepatitis A is the most common form and is passed on by the faecal– oral route. It’s tested for by the presence of the anti-HAV IgM antibody which tests positive before the development of clinical hepatitis and remains positive for at least 4months. Hepatitis B is tested for by the presence of surface antigen HBsAg. Anti HBC total and Anti – HBC IgM is also tested for. A soluble protein HBeAg is produced by the virus in acute and early chronic stages of hepatitis B so positivity of this indicates infection. Hepatitis C infection has the presentation of Anti-HCV seen in 90% of individuals with this infection [7]. The possibility of autoimmune hepatitis can be ruled out by testing of HLA class II expression on the surface of the hepatocytes. There is also an increase seen in IgG antibody and a variety of other antibodies such as SLA/LP (anti soluble liver protein) [8]. References [1] Hopkins. J. Alcoholic liver disease – Introduction, gastroenterology and hepatology. Baltimore M.D 2010 [2] www.britishlivertrust.org . Accessed 28.11.10 [3 ]Drriad. Pathogenesis of hepatitis infection from chronic alcoholism, Figure 1. 2007 [4] www.hepatitis.org. Phillipe.L, Hepatogastroenterology department, Brugmann University Hospital Brussells Accessed 28.11.10 [5]http://www.gastro.com/Gastro/liverdisease/liver_function.aspx, Gardner. P.W and Waldstreicher.W, American Liver Foundation 1995 Accessed 28.11.10 [6] Borzio. M et al, Thyroid function tests in chronic liver disease: evidence for multiple abnormalities despite clinical euthyroidism. GUT Journal of gastroenterology and hepatology, Vol 24(7), Jul 1983. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420033/. Accessed 28/11/10 [7] http://www.oaml.com/PDF/CLP012.pdf. Guidelines for clinical laboratory practice, revised March 2000, Accessed 28.11.10 [8]Krawitt. E.L Autoimmune hepatitis: classification, heterogeneity, and treatment, January 1994. Am. J. Med. Vol 96 (1A): 23S–26S. How to cite Critical Study of Alcohol and Hepatocytes Cell Necrosis, Essay examples

Critical Study of Alcohol and Hepatocytes Cell Necrosis Free Essays

Introduction The tissue shows vast inflammation, there are large gaps in between the hepatocytes due to cell necrosis and the hepatocytes remaining are large and swollen. There are fatty deposits throughout the tissue and fibrous structures present which are most likely collagen. The hepatocytes themselves are not only swollen but have the presence of globular material within. We will write a custom essay sample on Critical Study of Alcohol and Hepatocytes Cell Necrosis or any similar topic only for you Order Now This is identified as Mallory bodies, seen in cases of alcoholic hepatitis. These globules are aggregates of intermediate filaments in the cytoplasm which have resulted from hepatocyte injury. Neutrophils can be seen in the sample which is the likely cause of inflammation. These would have been called to the tissue due to the necrosis of the hepatocytes and the presence of cellular debris within the lobules [1]. An infiltration of macrophages can be seen which would also be due to the debris present. The first stage of alcoholic liver disease is the increase of fatty deposits in the liver. Heavy alcohol consumption causes the production of large fatty globules a process known as macrovesicular steatosis collecting in the liver cells. Ethanol consumed is metabolised by alcohol dehydrase in the mitochondria into toxic acetaldehyde which is metabolised by aldehyde dehydrogenase into acetic acid [1][2][3]. The production of acetaldehyde causes a higher NADH: NAD ratio which is the main mechanism in the development of this condition. This NADH production causes increase in lipogenesis and a decrease in fatty acid oxidation. The higher levels of fatty acids signal the hepatocytes to compound glycerol into triglycerides [3]. This is seen in the first stage of liver damage known as alcoholic hepatitis [2]. Excess alcohol intake can also cause hepatocyte injury via oxidative stress from increased NADH production in which free radicals damage the hepatocytes (increased production by the k upffer cells); and from lipid peroxidation where acetylhyde binds to proteins forming adducts [1]. This binding triggers humoral and cellular immune responses resulting in tissue injury. There is an increase in pro inflammatory cytokines such as tumour necrosis factor and interleukin -6 and a decrease in anti inflammatory cytokines such as interleukin -4 [1]. These cytokines in particularly TNF are secreted by the kupffer cells (macrophages) located in the liver. They’re activated by the increased levels of endotoxin released from the breakdown of alcohol by intestinal bacteria; this binds to the CD14 receptor on their surface initiating response. The release of these cytokines leads to the hepatic stellate cells producing increased levels of collagen which leads to liver fibrosis and also causes destructive damage to the hepatocytes. This leads to the last stage of liver disease known as cirrhosis which can occur in prolonged alcoholic hepatitis, seen in 40% of cases [1][4] . Individuals suffering with alcoholic hepatitis have an increase in serum bilirubin due to the inability of the damaged liver to process it. Bilirubin is normally removed from the blood by the liver, processed by it and released into the bile [4][5]. They’ll also have prolonged prothrombin time which reflects decreased hepatic synthetic function [4][5]. A number of clotting factor proteins are produced in the liver so an increase in coagulation time suggests a decrease in these factors indicating dysfunction of the liver. Decreased serum albumin can be observed in cases of liver injury as this is the main protein produced in the liver. Thyroid tests can indicate liver dysfunction such as testing for T3- triiodothrynonine which appears decreased in individuals with alcoholic hepatitis and is proportional to the level of damage[6][4]. There is also a decrease in serum cholesterol level seen in this condition. In cases where excessive alcohol consumption is not the cause of hepatitis further testing should be done. Individuals can develop hepatitis due to drug use as currently 1000 drugs are seen to be hepatotoxic [7]. There must be a chronic correlation seen between when the medicine was first taken and the observation of hepatitis. There must also be a correlation between the removal of medication and the recession of the condition [4]. Other causes of hepatitis must also be tested for such as viral hepatitis. There are 5 subsets of viral hepatitis A, B, C, and the less common D and E forms. Hepatitis A is the most common form and is passed on by the faecal– oral route. It’s tested for by the presence of the anti-HAV IgM antibody which tests positive before the development of clinical hepatitis and remains positive for at least 4months. Hepatitis B is tested for by the presence of surface antigen HBsAg. Anti HBC total and Anti – HBC IgM is also tested for. A soluble protein HBeAg is produced by the virus in acute and early chronic stages of hepatitis B so positivity of this indicates infection. Hepatitis C infection has the presentation of Anti-HCV seen in 90% of individuals with this infection [7]. The possibility of autoimmune hepatitis can be ruled out by testing of HLA class II expression on the surface of the hepatocytes. There is also an increase seen in IgG antibody and a variety of other antibodies such as SLA/LP (anti soluble liver protein) [8]. References [1] Hopkins. J. Alcoholic liver disease – Introduction, gastroenterology and hepatology. Baltimore M.D 2010 [2] www.britishlivertrust.org . Accessed 28.11.10 [3 ]Drriad. Pathogenesis of hepatitis infection from chronic alcoholism, Figure 1. 2007 [4] www.hepatitis.org. Phillipe.L, Hepatogastroenterology department, Brugmann University Hospital Brussells Accessed 28.11.10 [5]http://www.gastro.com/Gastro/liverdisease/liver_function.aspx, Gardner. P.W and Waldstreicher.W, American Liver Foundation 1995 Accessed 28.11.10 [6] Borzio. M et al, Thyroid function tests in chronic liver disease: evidence for multiple abnormalities despite clinical euthyroidism. GUT Journal of gastroenterology and hepatology, Vol 24(7), Jul 1983. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420033/. Accessed 28/11/10 [7] http://www.oaml.com/PDF/CLP012.pdf. Guidelines for clinical laboratory practice, revised March 2000, Accessed 28.11.10 [8]Krawitt. E.L Autoimmune hepatitis: classification, heterogeneity, and treatment, January 1994. Am. J. Med. Vol 96 (1A): 23S–26S. How to cite Critical Study of Alcohol and Hepatocytes Cell Necrosis, Essay examples

Saturday, April 25, 2020

Of All The Scientists To Emerge From The Nineteenth And Twentieth Cent

Of all the scientists to emerge from the nineteenth and twentieth centuries there is one whose name is known by almost all living people. While most of these do not understand this man's work, everyone knows that its impact on the world of science is astonishing. Yes, many have heard of Albert Einstein's General Theory of relativity, but few know about the intriguing life that led this scientist to discover what some have called, "The greatest single achievement of human thought." Einstein was born in Ulm, Germany on March 14, 1874. Before his first birthday, his family had moved to Munich where young Albert's father, Hermann Einstein, and uncle set up a small electro-chemical business. He was fortunate to have an excellent family with which he held a strong relationship. Albert's mother, Pauline Einstein, had an intense passion for music and literature, and it was she that first introduced her son to the violin in which he found much joy and relaxation. Also, he was very close with his younger sister, Maja, and hey could often be found in the lakes that were scattered about the countryside near Munich. As a child, Einstein's sense of curiosity had already begun to stir. A favorite toy of his was his father's compass, and he often marvelled at his uncle's explanations of algebra. Although young Albert was intrigued by certain mysteries of science, he was considered a slow learner. His failure to become fluent in German until the age of nine even led some teachersto believe he was disabled. Einstein's post-basic education began at the Luitpold Gymnasium when he was ten. It was here that he first encountered the German spirit through the school's strict disciplinary policy. His disapproval of this method of teaching led to his reputation as a rebel. It was probably these differences that caused Einstein to search for knowledge at home. He began not with science, but with religion. He avidly studied the Bible seeking truth, but this religious fervor soon died down when he discovered the intrigue of science and math. To him, these seemed much more realistic than ancient stories. With this new knowledge he disliked class even more, and was eventually expelled from Luitpold Gymnasium being considered a disruptive influence. Feeling that he could no longer deal with the German mentality, Einstein moved to Switzerland where he continued his education. At sixteen he attempted to enroll at the Federal Institute of Technology but failed the entrance exam. This forced him to study locally for one year until he finally passed the school's evaluation. The Institute allowed Einstein to meet many other students that shared his curiosity, and It was here that his studies turned mainly to Physics. He quickly learned that while physicists had generally agreed on major principals in the past, there were modern scientists who were attempting to disprove outdated theories. Since most of Einstein's teachers ignored these new ideas, he was again forced to explore on his own. In 1900 he graduated from the Institute and then achieved citizenship to Switzerland. Einstein became a clerk at the Swiss Patent Office in 1902. This job had little to do with physics, but he was able to satiate his curiosity by figuring out how new inventions worked. The most important part of Einstein's occupation was that it allowed him enough time to pursue his own line of research. As his ideas began to develop, he published them in specialist journals. Though he was still unknown to the scientific world, he began to attract a large circle of friends and admirers. A group of students that he tutored quickly transformed into a social club that shared a love of nature, music, and of course, science. In 1903 he married Mileva Meric, a mathematician friend. In 1905, Einstein published five separate papers in a journal, the Annals of Physics. The first was immediately acknowledged, and the University of Zurich awarded Einstein an additional degree. The other papers helped to develop modern physics and earned him the reputation of an artist. Many scientists have said that Einstein's work contained an imaginative spirit that was seen in most poetry. His work at this time dealt with molecules, and how their motion affected temperature, but he is

Wednesday, March 18, 2020

What Xenophobia Is With Examples

What Xenophobia Is With Examples Xenophobia is as ubiquitous as the common cold. It shapes public policy, drives political campaigns and even sparks hate crimes. Yet, the meaning of this multi-syllabic word remains a mystery to many of the people who adopt xenophobic attitudes or find themselves subjected to them. This review of xenophobia illuminates the practice with a definition, contemporary and historical examples and an analysis of how xenophobia intersects with racism. What Xenophobia Is Pronounced zeen-oh-fobe-ee-ah, xenophobia is the fear or contempt of foreign people, places or things. People with this â€Å"fear† are known as xenophobes and the attitudes they have as xenophobic. While phobia refers to fear, xenophobes aren’t scared of foreign people in the same way that a person with arachnophobia fears spiders. Instead, their â€Å"fear† can best be compared to homophobia, as hatred largely drives their repulsion to foreigners.   Xenophobia can occur anywhere. In the United States, known for being the land of immigrants, a number of groups have been the targets of xenophobia, including the Italians, Irish, Poles, Slavs, Chinese, Japanese and a variety of immigrants from Latin America. As a result of xenophobia, immigrants from these backgrounds and others faced discrimination in employment, housing, and other sectors. The U.S. government even passed laws to restrict the number of Chinese nationals in the country and to strip Japanese Americans from the country’s coasts. The Chinese Exclusion Act and Executive Order 9066 More than 200,000 Chinese nationals traveled to the U.S. after the gold rush of 1849. In a three-decade period, they became 9 percent of California’s population and a quarter of the state’s labor force, according to the second volume of America’s History. Although whites excluded the Chinese from higher-wage jobs, the immigrants from the East made a name for themselves in industries such as cigar-making. Before long, white workers came to resent the Chinese and actually threatened to burn the docks from which these newcomers arrived in the U.S. The slogan â€Å"The Chinese Must Go!† became a rallying cry for Californians with anti-Chinese biases. In 1882, Congress passed the Chinese Exclusion Act to halt the migration of Chinese nationals into the U.S. America’s History describes how xenophobia fueled this decision. â€Å"In other parts of the country, popular racism was directed against African Americans; in California (where blacks were few in number) it found a target in the Chinese. They were an ‘infusible’ element who could not be assimilated into American society, wrote the young journalist Henry George in a famous 1869 letter that made his reputation as a spokesman for California labor. ‘They practice all the unnameable vices of the East. [They are] utter heathens, treacherous, sensual, cowardly and cruel.’† George’s words perpetuate xenophobia by casting the Chinese and their homeland as vice-ridden and, thus, threatening to the U.S. As George framed them, the Chinese were untrustworthy and inferior to Westerners. Such xenophobic opinions not only kept Chinese workers on the sidelines of the labor force and dehumanized them but also led to U.S. lawmakers banning Chinese immigrants from entering the country. The Chinese Exclusion Act is far from the only U.S. legislation passed with xenophobic roots. Just months after the Japanese bombed Pearl Harbor on Dec. 7, 1941, President Franklin D. Roosevelt signed Executive Order 9066, allowing the federal government to force more than 110,000 Japanese Americans on the West Coast from their homes and into internment camps. He signed the order under the guise that any American of Japanese descent was a potential threat to the U.S., as they could join forces with Japan to commit espionage or other attacks against the country. Historians point out, however, that anti-Japanese sentiment in places such as California fueled the move. The president had no reason to view Japanese Americans as threats, especially since the federal government never linked any such person to espionage or plots against the U.S.   The U.S. appeared to make some headway in its treatment of immigrants in 1943 and 1944, when it, respectively, repealed the Chinese Exclusion Act and allowed Japanese American internees to return to their homes. More than four decades later, President Ronald Reagan signed the Civil Liberties Act of 1988, which offered a formal apology to Japanese American internees and a payout of $20,000 to internment camp survivors. It took until June 2012 for the U.S. House of Representatives to pass a resolution apologizing for the Chinese Exclusion Act. Proposition 187 and SB 1070 Xenophobic public policy isn’t limited to the anti-Asian legislation of America’s past. More recent laws, such as California’s Proposition 187 and Arizona’s SB 1070, have also been labeled xenophobic for striving to create a sort of police state for undocumented immigrants in which they’d constantly be under scrutiny and denied basic social services. Named the Save Our State initiative, Prop. 187 aimed to bar undocumented immigrants from receiving public services such as education or medical treatment. It also mandated teachers, healthcare workers, and others to report individuals they suspected of being undocumented to the authorities. Although the ballot measure passed with 59 percent of the vote, federal courts later struck it down for being unconstitutional. Sixteen years after the controversial passage of California’s Prop. 187, the Arizona legislature passed SB 1070, which required police to check the immigration status of anyone they suspected to be in the country illegally. This mandate, predictably, led to concerns about racial profiling. In 2012, the U.S. Supreme Court ultimately gutted some parts of the law, including the provision allowing police to arrest immigrants without probable cause and the provision making it a state crime for unauthorized immigrants not to carry registration papers at all times. The high court, however, left in the provision allowing authorities to check a person’s immigration status while enforcing other laws if they have reasonable cause to believe the individuals reside in the U.S. illegally. While that marked a small victory for the state, Arizona suffered a highly publicized boycott because of its immigration policy. The city of Phoenix lost $141 million in tourism revenue as a result, according to the Center for American Progress.   How Xenophobia and Racism Intersect Xenophobia and racism often coexist. While whites have been targets of xenophobia, such whites usually fall into the â€Å"white ethnic† category- Slavs, Poles, Jews. In other words, they’re not white Anglo-Saxon Protestants, the Western Europeans historically deemed as desirable whites. In the early 20th century, prominent whites expressed fear that white ethnics were reproducing at higher rates than the WASP population. In the 21st century, such fears continue to be raised. Roger Schlafly, son of Phyllis Schlafly, founder of the conservative political group Eagle Forum,  Ã‚  expressed his dismay in 2012 about a New York Times article that covered the rise of the Latino birthrate and the dip in the white birthrate. He lamented the growing number of immigrants with little in common with the 1950s American family, which he describes as â€Å"happy, self-sufficient, autonomous, law-abiding, honorable, patriotic, hard-working.†   In contrast, according to Schlafly, Latino immigrants are transforming the U.S. to its detriment. They â€Å"do not share those values, and †¦ have high rates of illiteracy, illegitimacy, and gang crime, and they will vote Democrat when the Democrats promise them more food stamps.† In short, because Latinos aren’t 1950s WASPs, they must be bad news for the U.S. Just as blacks have been characterized as welfare dependent, Schlafly argues that Latinos are too and will flock to Democrats for â€Å"food stamps.† Wrapping Up While white ethnics, Latinos and other immigrants of color face negative stereotypes, Americans typically hold Western Europeans in high regard. They praise the British for being cultured and refined and the French for their cuisine and fashion. Immigrants of color, however, routinely fight off the idea that they’re inferior to whites. They lack intelligence and integrity or bring disease and crime into the country, xenophobes claim. Sadly, more than 100 years after the passage of the Chinese Exclusion Act, xenophobia remains prevalent in U.S. society.

Sunday, March 1, 2020

7 Tips to Learn New Skills Fast

7 Tips to Learn New Skills Fast Everybody has their own reasons to learn new skills. Some need them for work, some because of the changes, caused by various life events, some choose to do it just because its fun. Wherever your motivation lies, mastering a new skill in a quicker and more efficient way will certainly benefit you. Weve collected 7 tips to help you do this. Pick the one to your liking or try combining all of them! Stare Steal In the vast majority of cases learning a new skill is not a matter of being naturally gifted. Its rather a combination of perseverance and practice. The research suggests, that to get started on this way you are to do two highly important things: stare at people doing something you want to learn and dont hesitate to use your observations in practice. Go to master classes, recitals or tournaments and turn them into a study session from an entertaining activity. Staring means close examining of what helps a person do something proficiently. Stealing is using these little details in your own activities. For instance, if you aim at learning how to play the piano – watch the moves of the musician and do your very best to notice special tilt of the wrist and the way they touch those ivories. And when you go back home, mimic the manners. This principle applies to lots of spheres of activities. Take it and use it. Deconstruct Learning a new skill gets far more manageable when you dissect it into several constituents. A functional model of doing this in an effective way was suggested by Tim Ferris, an expert on learning issues. He has come up with DiSSS system: Deconstruction, Selection, Sequencing and Stakes. So, first you have to break down the skill into small bricks. Then you choose the way of applying 20% of effort, thats going to bring 80% result. Next, you are to think of the best order to learn the blocks of the skill. Last but not least, you need to come up with a system of praise and punishment, thats going to motivate you to actually go all the way through. Lets say your goal is learning how to play the guitar. To begin, you need to learn a set of chords, necessary to play a couple of your favorite songs. Having looked through the list, you may range them from the easiest to the most complicated ones. Then, start practicing, gradually increasing the difficulty level. Dont stop until youve come to the first evident result. Once youre there – throw a little party and perform for your guests. If youre not – dont go out until you reach the needed result. See? DiSSS in action! Dont Be Afraid to Be Stupid Thats one of the most common fears. Dont let it stand in the way of your learning new, amazing things. Ask questions and make mistakes – thats a sure recipe of getting not theoretical knowledge, but hands-on experience, which is a much shorter way to succeeding in a new area. Dont hesitate to take risks and make scary decisions. Going the safe, correct way may deprive you of the opportunity to engage into an interesting journey, that will actually be far more beneficial in the end. Who knows, maybe the stupid question you ask on the forum will lead to unexpected fascinating circumstances? Maybe the way you cook that meal is even better than the original recipe? Be a daring explorer and have fun with it. â€Å"No† to Routine The study has shown, that changing the way of practice is more advantageous than mere repetition of the action. The participants were asked to attend several training sessions, aimed at teaching them to move a cursor with the help of a device, that responded to squeezing. Representatives of one group were asked to perform different exercises during the sessions, while people from the other one stuck to a single exercise pattern. In the end, participants from the first batch showed better results, having demonstrated higher level of ability to adjust to new conditions as well as better overall performance. Although the research concentrated on motor skills, the approach is applicable to other ones just as well. For example, when you learn a new language, you may either simply repeat and revise new words or use them in different constructions or word games. In fact, youll see the benefits of the second method quite soon. Dont Make Things Difficult Thats simply a matter of common sense. The best practices of learning the skill youve chosen have probably already been established. So dont reinvent the wheel. Watch a couple of YouTube tutorials or go through articles, devoted to the topic. It never hurts to use others experience. Once you learn the basics, youll get a chance to create your own routes. Be a Doer, Not Just a Learner Going through theoretical basis is definitely a good start. However, if youve decided that to learn the skill you need to read 10 classic books, devoted to the topic, you are most probably wrong. If you dont see the first result of your practice soon, youre very likely to lose all the interest. Dont let this happen. So, if you want to learn how to cook, for example, get down to business as soon as possible. You may seek inspiration from different sources later. However, at the starting point you need to be as down-to-earth as possible. Cook that salad and youll get to the bouillabaisse faster. Discomfort Is a Friend People love being comfortable. Nevertheless, relaxation is not good if you want to master a new ability quickly. Your brain feels that the environment is safe and warm, thus, you shouldnt try any harder. Thats why putting yourself in rather tough conditions is actually good. The best-performing schools and training facilities often look pretty basic and definitely are far from luxury. So, dont get too comfy and try to avoid distractions. This technique will facilitate learning, enhance your performance and make you even happier, when you praise yourself with a little something, having made progress. Learning is an adventure, where the prizes are guaranteed, in case you pay enough effort and diligence. Have an awesome one!